High-throughput RNA sequencing of paraformaldehyde-fixed single cells
H.V. Phan, M. van Gent, N. Drayman, A. Basu, M.U. Gack, & S. Tay. (2021) Nat Comm 12(1): 5636.
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
N. Drayman, J.K. DeMarco, K.A. Jones, S.A. Azizi, H.M. Froggatt, K. Tan, N.I. Maltseva, S. Chen, V. Nicolaescu, S. Dvorkin, K. Furlong, R.S. Kathayat, M.R. Firpo, V. Mastrodomenico, E.A. Bruce, M.M. Schmidt, R. Jedrzejczak, M.Á. Muñoz-Alía, B. Schuster, V. Nair, K.Y. Han, A. O’Brien, A. Tomatsidou, B. Meyer, M. Vignuzzi, D. Missiakas, J.W. Botten, C.B. Brooke, H. Lee, S.C. Baker, B.C. Mounce, N.S. Heaton, W.E. Severson, K.E. Palmer, B.C. Dickinson, A. Joachimiak, G. Randall, S. Tay. (2021) Science 373(6557): 931-936.
COVIDomic: A multi-modal cloud-based platform for identification of risk factors associated with COVID-19 severity
V. Naumov, E. Putin, S. Pushkov, E. Kozlova, K. Romantsov, A. Kalashnikov, F. Galkin, N. Tihonova, A. Shneyderman, E. Galkin, A. Zinkevich, S.M. Cope, R. Sethuraman, T.I. Oprea, A.T. Pearson, S. Tay, N. Agrawal, A. Dubovenko, Q. Vanhaelen, I. Ozerov, A. Aliper, E. Izumchenko, & A. Zhavoronkov. (2021) PLoS Comput Biol 17(7): e1009183.
Single-Cell Proteomics
L.F. Vistain & S. Tay. (2021) Trends Biochem Sci 46(8): 661-672.
NF-κB responds to absolute differences in cytokine concentrations
M. Son, A.G. Wang, H.L. Tu, M.O. Metzig, P. Patel, K. Husain, J. Lin, A. Murugan, A. Hoffmann, & S. Tay. (2021) Sci Signal 14(666): eaaz14882.
Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids
B. Schuster, M. Junkin, S.S. Kashaf, I. Romero-Calvo, K. Kirby, J. Matthews, C.R. Weber, A. Rzhetsky, K.P. White, & S. Tay. (2020) Nat Comm 11: 5271.
Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes
M.F. Abasıyanık, K. Wolfe, H.V. Phan, J. Lin, B. Laxman, S.R. White, P.A. Verhoef, G.M. Mutlu, B. Patel, & S. Tay. (2020) Nat Comm 11: 2607.
Ultra-sensitive digital quantification of proteins and mRNA in single cells
J. Lin, C. Jordi, M. Son, H.V. Phan, N. Drayman, M.F. Abasiyanik, L. Vistain, H.L. Tu, & S. Tay. (2019) Nat Comm 10: 3544.
Savas Tay, Ph.D.
Professor of Molecular Engineering
- Contact: tays@uchicago.edu