Black-and-white headshot of Aaron Esser-Kahn

Aaron P. Esser-Kahn, Ph.D.

Improving the Adjuvanticity of Small Molecule Immune Potentiators Using Covalently Linked NF-κB Modulators

F.W. Kimani, S. Manna, B. Moser, J. Shen, N. Nihesh, & A.P. Esser-Kahn. (2021) ACS Med Chem Lett 12(9): 1441-1448.

A synthetic pathogen mimetic molecule induces a highly amplified synergistic immune response via activation of multiple signaling pathways

N. Nihesh, S. Manna, B. Studnitzer, J. Shen, & A.P. Esser-Kahn. (2021) Chem Sci 12(19): 6646-6651

Site-specific antigen-adjuvant conjugation using cell-free protein synthesis enhances antigen presentation and CD8+ T-cell response

A.M. Weiss, J. Ajit, T.J. Albin, N. Kapoor, S. Maroju, A. Berges, L. Pill, J. Fairman & A.P. Esser-Kahn. (2021) Sci Rep 11: 6267.

Bio-inspired mechanically adaptive materials through vibration-induced crosslinking

Z. Wang, J. Wang, J. Ayarza, T. Steeves, Z. Hu, S. Manna, & A.P. Esser‐Kahn. (2021) Nat Mater 20: 869-874.

Pathogen-like Nanoassemblies of Covalently Linked TLR Agonists Enhance CD8 and NK Cell-Mediated Antitumor Immunity

S. Manna, S. Maiti, J. Shen, W. Du, & A.P. Esser-Kahn. (2020) ACS Cent Sci 6(11): 2071-2078.

Increased vaccine tolerability and protection via NF-κB modulation

B.A. Moser, R.C. Steinhardt, Y. Escalante-Buendia, D. A. Boltz, K. M. Barker, B. J. Cassaidy, M.G. Rosenberger, S. Yoo, B. G. McGonnigal, & A. P. Esser-Kahn. (2020) Sci Adv 6(37): eaaz8700.

Tuning Subunit Vaccines with Novel TLR Triagonist Adjuvants to Generate Protective Immune Responses against Coxiella burnetii

A.P. Gilkes, T.J. Albin, S. Manna, M. Supnet, S. Ruiz, J. Tom, A.J. Badten, A. Jain, R. Nakajima, J. Felgner, D.H. Davies, S.A. Stetkevich, A. Zlotnik, E. Pearlman, A. Nalca, P.L. Felgner, A.P. Esser-Kahn & A.M. Burkhardt. (2020) J Immunol 204(3): 611-621.

Correlating the structure and reactivity of a contact allergen, DNCB, and its analogs to sensitization potential

F. Kimani, S.M. Kim, R. Steinhardt, & A.P. Esser-Kahn. (2019) Bioorg Med Chem 27(13): 2985-2990.

Linked Toll-Like Receptor Triagonists Stimulate Distinct, Combination-Dependent Innate Immune Responses

T.J. Albin, J.K. Tom, S. Manna, A.P. Gilkes, S.A. Stetkevich, B.B. Katz, M. Supnet, J. Felgner, A. Jain, R. Nakajima, A. Jasinskas, A. Zlotnik, E. Pearlman, D.H. Davies, P.L. Felgner, A.M. Burkhardt, & A.P. Esser-Kahn. (2019) ACS Cent Sci 5(7): 1137-1145.